The following units have the capability to support custom routes.
Quest/Quest 2
StreetPilot 2600, 2700, 2800, 7200, and 7500 series
Any Zumo unit
Nuvi 500, 700, 705, 800, 805, 1400, 1600, 2200, 2300, and 3700 series
Any of these units will be able to support custom routes, though some can support more than others. However, the absolute minimum number of routes is 10 with any of these units, so you can set up at least 10 routes if not more.